WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:glycosphingolipid metabolic process       ID:GO:0006687
C=61; O=3; E=0.24; R=12.41; rawP=0.0018; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
3  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422


Database:biological process       Name:protein lipidation       ID:GO:0006497
C=55; O=3; E=0.22; R=13.76; rawP=0.0013; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
2  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
3  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599


Database:biological process       Name:carbohydrate derivative metabolic process       ID:GO:1901135
C=1211; O=13; E=4.80; R=2.71; rawP=0.0007; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
2  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
3  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
6  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
7  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
8  ENSG00000132329 NA RAMP1 receptor (G protein-coupled) activity modifying protein 1 10267 ENSG00000132329
9  ENSG00000103152 NA MPG N-methylpurine-DNA glycosylase 4350 ENSG00000103152
10  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
11  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
12  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830
13  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:biological process       Name:protein palmitoylation       ID:GO:0018345
C=12; O=2; E=0.05; R=42.04; rawP=0.0010; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
2  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599


Database:biological process       Name:lipoprotein biosynthetic process       ID:GO:0042158
C=60; O=3; E=0.24; R=12.61; rawP=0.0017; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
2  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
3  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599


Database:biological process       Name:glycolipid metabolic process       ID:GO:0006664
C=102; O=4; E=0.40; R=9.89; rawP=0.0007; adjP=0.1167
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
3  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
4  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422


Database:biological process       Name:response to pH       ID:GO:0009268
C=25; O=2; E=0.10; R=20.18; rawP=0.0044; adjP=0.1712
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000122986 NA HVCN1 hydrogen voltage-gated channel 1 84329 ENSG00000122986
2  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730


Database:biological process       Name:glycoprotein metabolic process       ID:GO:0009100
C=387; O=6; E=1.53; R=3.91; rawP=0.0042; adjP=0.1712
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
2  ENSG00000132329 NA RAMP1 receptor (G protein-coupled) activity modifying protein 1 10267 ENSG00000132329
3  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
6  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:biological process       Name:membrane lipid metabolic process       ID:GO:0006643
C=164; O=4; E=0.65; R=6.15; rawP=0.0040; adjP=0.1712
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
3  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
4  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422


Database:biological process       Name:chondroitin sulfate biosynthetic process       ID:GO:0030206
C=25; O=2; E=0.10; R=20.18; rawP=0.0044; adjP=0.1712
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
2  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:molecular function       Name:catalytic activity       ID:GO:0003824
C=5371; O=34; E=19.68; R=1.73; rawP=8.18e-05; adjP=0.0092
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
3  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599
4  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
5  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
6  ENSG00000141639 NA MAPK4 mitogen-activated protein kinase 4 5596 ENSG00000141639
7  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
8  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
9  ENSG00000176014 NA TUBB6 tubulin, beta 6 class V 84617 ENSG00000176014
10  ENSG00000089248 NA ERP29 endoplasmic reticulum protein 29 10961 ENSG00000089248
11  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
12  ENSG00000181396 NA C17orf101 chromosome 17 open reading frame 101 79701 ENSG00000181396
13  ENSG00000109079 NA TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 7126 ENSG00000109079
14  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
15  ENSG00000100462 NA PRMT5 protein arginine methyltransferase 5 10419 ENSG00000100462
16  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
17  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243
18  ENSG00000170145 NA SIK2 salt-inducible kinase 2 23235 ENSG00000170145
19  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
20  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
21  ENSG00000134333 NA LDHA lactate dehydrogenase A 3939 ENSG00000134333
22  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
23  ENSG00000103152 NA MPG N-methylpurine-DNA glycosylase 4350 ENSG00000103152
24  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
25  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
26  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
27  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
28  ENSG00000147485 NA PXDNL peroxidasin homolog (Drosophila)-like 137902 ENSG00000147485
29  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
30  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
31  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
32  ENSG00000144647 NA GTDC2 glycosyltransferase-like domain containing 2 84892 ENSG00000144647
33  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830
34  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736


Database:molecular function       Name:L-ascorbic acid binding       ID:GO:0031418
C=21; O=2; E=0.08; R=25.99; rawP=0.0026; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
2  ENSG00000181396 NA C17orf101 chromosome 17 open reading frame 101 79701 ENSG00000181396


Database:molecular function       Name:ATPase activity, coupled to movement of substances       ID:GO:0043492
C=98; O=3; E=0.36; R=8.35; rawP=0.0055; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:molecular function       Name:P-P-bond-hydrolysis-driven transmembrane transporter activity       ID:GO:0015405
C=106; O=3; E=0.39; R=7.72; rawP=0.0069; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:molecular function       Name:carbohydrate binding       ID:GO:0030246
C=269; O=5; E=0.99; R=5.07; rawP=0.0030; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
2  ENSG00000070413 NA DGCR2 DiGeorge syndrome critical region gene 2 9993 ENSG00000070413
3  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
4  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
5  ENSG00000181396 NA C17orf101 chromosome 17 open reading frame 101 79701 ENSG00000181396


Database:molecular function       Name:primary active transmembrane transporter activity       ID:GO:0015399
C=106; O=3; E=0.39; R=7.72; rawP=0.0069; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:molecular function       Name:ATPase activity, coupled to transmembrane movement of substances       ID:GO:0042626
C=97; O=3; E=0.36; R=8.44; rawP=0.0054; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:molecular function       Name:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances       ID:GO:0016820
C=100; O=3; E=0.37; R=8.19; rawP=0.0059; adjP=0.0966
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
2  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
3  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553


Database:molecular function       Name:transferase activity, transferring sulfur-containing groups       ID:GO:0016782
C=60; O=2; E=0.22; R=9.10; rawP=0.0204; adjP=0.1864
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
2  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119


Database:molecular function       Name:transferase activity       ID:GO:0016740
C=1756; O=12; E=6.43; R=1.87; rawP=0.0233; adjP=0.1864
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170145 NA SIK2 salt-inducible kinase 2 23235 ENSG00000170145
2  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
3  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599
6  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
7  ENSG00000141639 NA MAPK4 mitogen-activated protein kinase 4 5596 ENSG00000141639
8  ENSG00000100462 NA PRMT5 protein arginine methyltransferase 5 10419 ENSG00000100462
9  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
10  ENSG00000144647 NA GTDC2 glycosyltransferase-like domain containing 2 84892 ENSG00000144647
11  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
12  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:cellular component       Name:cytoplasmic part       ID:GO:0044444
C=6772; O=45; E=26.61; R=1.69; rawP=4.91e-06; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000144736 NA SHQ1 SHQ1 homolog (S. cerevisiae) 55164 ENSG00000144736
3  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
6  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
7  ENSG00000084090 NA STARD7 StAR-related lipid transfer (START) domain containing 7 56910 ENSG00000084090
8  ENSG00000177697 NA CD151 CD151 molecule (Raph blood group) 977 ENSG00000177697
9  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
10  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
11  ENSG00000089248 NA ERP29 endoplasmic reticulum protein 29 10961 ENSG00000089248
12  ENSG00000078808 NA SDF4 stromal cell derived factor 4 51150 ENSG00000078808
13  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
14  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
15  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
16  ENSG00000105290 NA APLP1 amyloid beta (A4) precursor-like protein 1 333 ENSG00000105290
17  ENSG00000109079 NA TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 7126 ENSG00000109079
18  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
19  ENSG00000100462 NA PRMT5 protein arginine methyltransferase 5 10419 ENSG00000100462
20  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
21  ENSG00000031081 NA ARHGAP31 Rho GTPase activating protein 31 57514 ENSG00000031081
22  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
23  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243
24  ENSG00000170145 NA SIK2 salt-inducible kinase 2 23235 ENSG00000170145
25  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
26  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
27  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
28  ENSG00000134333 NA LDHA lactate dehydrogenase A 3939 ENSG00000134333
29  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
30  ENSG00000137207 NA YIPF3 Yip1 domain family, member 3 25844 ENSG00000137207
31  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
32  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
33  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
34  ENSG00000104805 NA NUCB1 nucleobindin 1 4924 ENSG00000104805
35  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
36  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
37  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
38  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
39  ENSG00000008853 NA RHOBTB2 Rho-related BTB domain containing 2 23221 ENSG00000008853
40  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
41  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
42  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
43  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830
44  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
45  ENSG00000148498 NA PARD3 par-3 partitioning defective 3 homolog (C. elegans) 56288 ENSG00000148498


Database:cellular component       Name:endoplasmic reticulum       ID:GO:0005783
C=1282; O=16; E=5.04; R=3.18; rawP=2.72e-05; adjP=0.0014
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
3  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
4  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
5  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
6  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
7  ENSG00000089248 NA ERP29 endoplasmic reticulum protein 29 10961 ENSG00000089248
8  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
9  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
10  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
11  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
12  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
13  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
14  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
15  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
16  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243


Database:cellular component       Name:Golgi apparatus       ID:GO:0005794
C=1180; O=15; E=4.64; R=3.24; rawP=4.15e-05; adjP=0.0014
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000104805 NA NUCB1 nucleobindin 1 4924 ENSG00000104805
3  ENSG00000170145 NA SIK2 salt-inducible kinase 2 23235 ENSG00000170145
4  ENSG00000105290 NA APLP1 amyloid beta (A4) precursor-like protein 1 333 ENSG00000105290
5  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
6  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
7  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
8  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
9  ENSG00000137207 NA YIPF3 Yip1 domain family, member 3 25844 ENSG00000137207
10  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
11  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
12  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
13  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
14  ENSG00000078808 NA SDF4 stromal cell derived factor 4 51150 ENSG00000078808
15  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989


Database:cellular component       Name:endomembrane system       ID:GO:0012505
C=1771; O=18; E=6.96; R=2.59; rawP=0.0001; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
2  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
3  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
4  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
5  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
6  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
7  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
8  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
9  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
10  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
11  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
12  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
13  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
14  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
15  ENSG00000148498 NA PARD3 par-3 partitioning defective 3 homolog (C. elegans) 56288 ENSG00000148498
16  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
17  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
18  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243


Database:cellular component       Name:membrane       ID:GO:0016020
C=7811; O=46; E=30.69; R=1.50; rawP=0.0001; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
3  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599
4  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
5  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
6  ENSG00000177697 NA CD151 CD151 molecule (Raph blood group) 977 ENSG00000177697
7  ENSG00000102181 NA CD99L2 CD99 molecule-like 2 83692 ENSG00000102181
8  ENSG00000180155 NA LYNX1 Ly6/neurotoxin 1 66004 ENSG00000180155
9  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
10  ENSG00000176014 NA TUBB6 tubulin, beta 6 class V 84617 ENSG00000176014
11  ENSG00000132329 NA RAMP1 receptor (G protein-coupled) activity modifying protein 1 10267 ENSG00000132329
12  ENSG00000078808 NA SDF4 stromal cell derived factor 4 51150 ENSG00000078808
13  ENSG00000181396 NA C17orf101 chromosome 17 open reading frame 101 79701 ENSG00000181396
14  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
15  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
16  ENSG00000196376 NA SLC35F1 solute carrier family 35, member F1 222553 ENSG00000196376
17  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
18  ENSG00000105290 NA APLP1 amyloid beta (A4) precursor-like protein 1 333 ENSG00000105290
19  ENSG00000122986 NA HVCN1 hydrogen voltage-gated channel 1 84329 ENSG00000122986
20  ENSG00000181264 NA TMEM136 transmembrane protein 136 219902 ENSG00000181264
21  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
22  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
23  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243
24  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
25  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
26  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
27  ENSG00000164124 NA TMEM144 transmembrane protein 144 55314 ENSG00000164124
28  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
29  ENSG00000137207 NA YIPF3 Yip1 domain family, member 3 25844 ENSG00000137207
30  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
31  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
32  ENSG00000022567 NA SLC45A4 solute carrier family 45, member 4 57210 ENSG00000022567
33  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
34  ENSG00000135956 NA TMEM127 transmembrane protein 127 55654 ENSG00000135956
35  ENSG00000104805 NA NUCB1 nucleobindin 1 4924 ENSG00000104805
36  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
37  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
38  ENSG00000070413 NA DGCR2 DiGeorge syndrome critical region gene 2 9993 ENSG00000070413
39  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
40  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
41  ENSG00000008853 NA RHOBTB2 Rho-related BTB domain containing 2 23221 ENSG00000008853
42  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
43  ENSG00000167930 NA ITFG3 integrin alpha FG-GAP repeat containing 3 83986 ENSG00000167930
44  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
45  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
46  ENSG00000148498 NA PARD3 par-3 partitioning defective 3 homolog (C. elegans) 56288 ENSG00000148498


Database:cellular component       Name:membrane part       ID:GO:0044425
C=6154; O=39; E=24.18; R=1.61; rawP=0.0002; adjP=0.0029
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
3  ENSG00000156599 NA ZDHHC5 zinc finger, DHHC-type containing 5 25921 ENSG00000156599
4  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
5  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
6  ENSG00000177697 NA CD151 CD151 molecule (Raph blood group) 977 ENSG00000177697
7  ENSG00000102181 NA CD99L2 CD99 molecule-like 2 83692 ENSG00000102181
8  ENSG00000180155 NA LYNX1 Ly6/neurotoxin 1 66004 ENSG00000180155
9  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
10  ENSG00000132329 NA RAMP1 receptor (G protein-coupled) activity modifying protein 1 10267 ENSG00000132329
11  ENSG00000181396 NA C17orf101 chromosome 17 open reading frame 101 79701 ENSG00000181396
12  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
13  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
14  ENSG00000196376 NA SLC35F1 solute carrier family 35, member F1 222553 ENSG00000196376
15  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
16  ENSG00000105290 NA APLP1 amyloid beta (A4) precursor-like protein 1 333 ENSG00000105290
17  ENSG00000122986 NA HVCN1 hydrogen voltage-gated channel 1 84329 ENSG00000122986
18  ENSG00000181264 NA TMEM136 transmembrane protein 136 219902 ENSG00000181264
19  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
20  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
21  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243
22  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
23  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
24  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
25  ENSG00000164124 NA TMEM144 transmembrane protein 144 55314 ENSG00000164124
26  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
27  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
28  ENSG00000137207 NA YIPF3 Yip1 domain family, member 3 25844 ENSG00000137207
29  ENSG00000022567 NA SLC45A4 solute carrier family 45, member 4 57210 ENSG00000022567
30  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
31  ENSG00000135956 NA TMEM127 transmembrane protein 127 55654 ENSG00000135956
32  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
33  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
34  ENSG00000070413 NA DGCR2 DiGeorge syndrome critical region gene 2 9993 ENSG00000070413
35  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
36  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
37  ENSG00000167930 NA ITFG3 integrin alpha FG-GAP repeat containing 3 83986 ENSG00000167930
38  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
39  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736


Database:cellular component       Name:vacuole       ID:GO:0005773
C=408; O=8; E=1.60; R=4.99; rawP=0.0002; adjP=0.0029
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
2  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
3  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
4  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
5  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
6  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
7  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830
8  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736


Database:cellular component       Name:cytoplasm       ID:GO:0005737
C=9130; O=50; E=35.87; R=1.39; rawP=0.0003; adjP=0.0039
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000158104 NA HPD 4-hydroxyphenylpyruvate dioxygenase 3242 ENSG00000158104
2  ENSG00000144736 NA SHQ1 SHQ1 homolog (S. cerevisiae) 55164 ENSG00000144736
3  ENSG00000116521 NA SCAMP3 secretory carrier membrane protein 3 10067 ENSG00000116521
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000100422 NA CERK ceramide kinase 64781 ENSG00000100422
6  ENSG00000071553 NA ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 537 ENSG00000071553
7  ENSG00000084090 NA STARD7 StAR-related lipid transfer (START) domain containing 7 56910 ENSG00000084090
8  ENSG00000177697 NA CD151 CD151 molecule (Raph blood group) 977 ENSG00000177697
9  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
10  ENSG00000141639 NA MAPK4 mitogen-activated protein kinase 4 5596 ENSG00000141639
11  ENSG00000135776 NA ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 23456 ENSG00000135776
12  ENSG00000176014 NA TUBB6 tubulin, beta 6 class V 84617 ENSG00000176014
13  ENSG00000089248 NA ERP29 endoplasmic reticulum protein 29 10961 ENSG00000089248
14  ENSG00000078808 NA SDF4 stromal cell derived factor 4 51150 ENSG00000078808
15  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
16  ENSG00000123989 NA CHPF chondroitin polymerizing factor 79586 ENSG00000123989
17  ENSG00000130528 NA HRC histidine rich calcium binding protein 3270 ENSG00000130528
18  ENSG00000105290 NA APLP1 amyloid beta (A4) precursor-like protein 1 333 ENSG00000105290
19  ENSG00000109079 NA TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 7126 ENSG00000109079
20  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
21  ENSG00000100462 NA PRMT5 protein arginine methyltransferase 5 10419 ENSG00000100462
22  ENSG00000147119 NA CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 56548 ENSG00000147119
23  ENSG00000031081 NA ARHGAP31 Rho GTPase activating protein 31 57514 ENSG00000031081
24  ENSG00000161671 NA EMC10 ER membrane protein complex subunit 10 284361 ENSG00000161671
25  ENSG00000100243 NA CYB5R3 cytochrome b5 reductase 3 1727 ENSG00000100243
26  ENSG00000170145 NA SIK2 salt-inducible kinase 2 23235 ENSG00000170145
27  ENSG00000110917 NA MLEC malectin 9761 ENSG00000110917
28  ENSG00000124155 NA PIGT phosphatidylinositol glycan anchor biosynthesis, class T 51604 ENSG00000124155
29  ENSG00000128294 NA TPST2 tyrosylprotein sulfotransferase 2 8459 ENSG00000128294
30  ENSG00000134333 NA LDHA lactate dehydrogenase A 3939 ENSG00000134333
31  ENSG00000023191 NA RNH1 ribonuclease/angiogenin inhibitor 1 6050 ENSG00000023191
32  ENSG00000092820 NA EZR ezrin 7430 ENSG00000092820
33  ENSG00000137207 NA YIPF3 Yip1 domain family, member 3 25844 ENSG00000137207
34  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
35  ENSG00000140859 NA KIFC3 kinesin family member C3 3801 ENSG00000140859
36  ENSG00000163812 NA ZDHHC3 zinc finger, DHHC-type containing 3 51304 ENSG00000163812
37  ENSG00000135956 NA TMEM127 transmembrane protein 127 55654 ENSG00000135956
38  ENSG00000104805 NA NUCB1 nucleobindin 1 4924 ENSG00000104805
39  ENSG00000105223 NA PLD3 phospholipase D family, member 3 23646 ENSG00000105223
40  ENSG00000163399 NA ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 476 ENSG00000163399
41  ENSG00000162434 NA JAK1 Janus kinase 1 3716 ENSG00000162434
42  ENSG00000147485 NA PXDNL peroxidasin homolog (Drosophila)-like 137902 ENSG00000147485
43  ENSG00000145730 NA PAM peptidylglycine alpha-amidating monooxygenase 5066 ENSG00000145730
44  ENSG00000008853 NA RHOBTB2 Rho-related BTB domain containing 2 23221 ENSG00000008853
45  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
46  ENSG00000125912 NA NCLN nicalin 56926 ENSG00000125912
47  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
48  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830
49  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
50  ENSG00000148498 NA PARD3 par-3 partitioning defective 3 homolog (C. elegans) 56288 ENSG00000148498


Database:cellular component       Name:lytic vacuole       ID:GO:0000323
C=345; O=7; E=1.36; R=5.16; rawP=0.0004; adjP=0.0041
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
3  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
4  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
5  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
6  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
7  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830


Database:cellular component       Name:lysosome       ID:GO:0005764
C=345; O=7; E=1.36; R=5.16; rawP=0.0004; adjP=0.0041
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064601 NA CTSA cathepsin A 5476 ENSG00000064601
2  ENSG00000101160 NA CTSZ cathepsin Z 1522 ENSG00000101160
3  ENSG00000197746 NA PSAP prosaposin 5660 ENSG00000197746
4  ENSG00000053918 NA KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 3784 ENSG00000053918
5  ENSG00000117984 NA CTSD cathepsin D 1509 ENSG00000117984
6  ENSG00000162736 NA NCSTN nicastrin 23385 ENSG00000162736
7  ENSG00000177830 NA CHID1 chitinase domain containing 1 66005 ENSG00000177830




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).